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The central unit within the 19S regulatory particle of the proteasome
The 26S proteasome is a multisubunit enzyme composed of a cylindrical catalytic core (20S) and a regulatory particle (19S) that together perform the essential degradation of cellular proteins tagged by ubiquitin. To date, however, substrate trajectory within the complex remains elusive. Here we desc...
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Main Authors: | , , , |
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Format: | Artigo |
Jezik: | Inglês |
Izdano: |
2008
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2481239/ https://ncbi.nlm.nih.gov/pubmed/18511945 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1427 |
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