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Linkage disequilibrium with predisposing DR3 haplotypes accounts for apparent effects of TNF and LTA polymorphisms on T1D susceptibility
Tumor necrosis factor (TNF) and lymphotoxin alpha (LTA) are immunomodulators that have been hypothesized to contribute to susceptibility to type 1 diabetes (T1D). Several polymorphisms in the TNF and LTA loci have been extensively studied for T1D association, with conflicting reports. In this study,...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2481238/ https://ncbi.nlm.nih.gov/pubmed/17174749 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.humimm.2006.10.002 |
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