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Amplification of EMSY Gene in a Subset of Sporadic Pancreatic Adenocarcinomas
Mutations in the breast cancer susceptibility gene 2 (BRCA2) are commonly found in familial pancreatic cancer. Recently, EMSY (11q13.5) has been described as a BRCA2 interacting protein capable of binding and inactivating the protein domain encoded by exon 3 of the BRCA2 gene. Amplification of EMSY...
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Principais autores: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
e-Century Publishing Corporation
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2480540/ https://ncbi.nlm.nih.gov/pubmed/18787609 |
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