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Amplification of EMSY Gene in a Subset of Sporadic Pancreatic Adenocarcinomas

Mutations in the breast cancer susceptibility gene 2 (BRCA2) are commonly found in familial pancreatic cancer. Recently, EMSY (11q13.5) has been described as a BRCA2 interacting protein capable of binding and inactivating the protein domain encoded by exon 3 of the BRCA2 gene. Amplification of EMSY...

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Detalhes bibliográficos
Principais autores: van Hattem, W Arnout, Carvalho, Ralph, Li, Ang, Offerhaus, G Johan A, Goggins, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2480540/
https://ncbi.nlm.nih.gov/pubmed/18787609
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