The immunogenicity of VP7, a rotavirus antigen resident in the endoplasmic reticulum, is enhanced by cell surface expression.

The glycoprotein VP7, the major serotype antigen of rotaviruses, is localized to the endoplasmic reticulum (ER) of the cell, where it is retained as a membrane-associated protein before assembly into mature virus particles. Wild-type VP7 expressed by a recombinant vaccinia virus was also located int...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Andrew, M E, Boyle, D B, Whitfeld, P L, Lockett, L J, Anthony, I D, Bellamy, A R, Both, G W
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1990
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC247965/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2168965/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.10.4776-4783.1990
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