The immunogenicity of VP7, a rotavirus antigen resident in the endoplasmic reticulum, is enhanced by cell surface expression.

The glycoprotein VP7, the major serotype antigen of rotaviruses, is localized to the endoplasmic reticulum (ER) of the cell, where it is retained as a membrane-associated protein before assembly into mature virus particles. Wild-type VP7 expressed by a recombinant vaccinia virus was also located int...

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Pubblicato in:	J Virol
Autori principali:	Andrew, M E, Boyle, D B, Whitfeld, P L, Lockett, L J, Anthony, I D, Bellamy, A R, Both, G W
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1990
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC247965/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2168965/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.10.4776-4783.1990
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