The immunogenicity of VP7, a rotavirus antigen resident in the endoplasmic reticulum, is enhanced by cell surface expression.

The glycoprotein VP7, the major serotype antigen of rotaviruses, is localized to the endoplasmic reticulum (ER) of the cell, where it is retained as a membrane-associated protein before assembly into mature virus particles. Wild-type VP7 expressed by a recombinant vaccinia virus was also located int...

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Bibliografiske detaljer

Udgivet i:	J Virol
Principais autores:	Andrew, M E, Boyle, D B, Whitfeld, P L, Lockett, L J, Anthony, I D, Bellamy, A R, Both, G W
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 1990
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC247965/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2168965/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.10.4776-4783.1990
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