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Ins1 Gene Up-Regulated in a β-Cell Line Derived from Ins2 Knockout Mice

The authors have derived a new β-cell line (βIns2(−/−lacZ)) from Ins2(−/−) mice that carry the lacZ reporter gene under control of the Ins2 promoter. βIns2(−/−lacZ) cells stained positively using anti-insulin antibody, expressed β-cell–specific genes encoding the transcription factor PDX-1, glucokin...

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Autors principals: Leroux, Loïc, Durel, Béatrice, Autier, Valérie, Deltour, Louise, Bucchini, Danielle, Jami, Jacques, Joshi, Rajiv L.
Format: Artigo
Idioma:Inglês
Publicat: 2003
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2479409/
https://ncbi.nlm.nih.gov/pubmed/12745665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15438600303730
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