Nicotinic acetylcholine receptor subunit variants are associated with blood pressure; findings in the Old Order Amish and replication in the Framingham Heart Study

BACKGROUND: Systemic blood pressure, influenced by both genetic and environmental factors, is regulated via sympathetic nerve activity. We assessed the role of genetic variation in three subunits of the neuromuscular nicotinic acetylcholine receptor positioned on chromosome 2q, a region showing repl...

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Detalhes bibliográficos
Main Authors: McArdle, Patrick F, Rutherford, Sue, Mitchell, Braxton D, Damcott, Coleen M, Wang, Ying, Ramachandran, Vasan, Ott, Sandy, Chang, Yen-Pei C, Levy, Daniel, Steinle, Nanette
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2478679/
https://ncbi.nlm.nih.gov/pubmed/18625075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-9-67
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