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A common non-synonymous variant in GLUT9 is a determinant of serum uric acid levels in Old Order Amish

OBJECTIVE: Uric acid is the primary end product of purine metabolism. Increased serum uric acid has been associated with gouty arthritis as well as with a variety of cardiovascular related phenotypes. METHODS: A 500,000 SNP genome wide association study of serum uric acid levels was performed in a c...

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Bibliografiske detaljer
Main Authors: McArdle, Patrick F., Parsa, Afshin, Chang, Yen-Pei C., Weir, Matthew R., O'Connell, Jeffery R., Mitchell, Braxton D., Shuldiner, Alan R.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2779583/
https://ncbi.nlm.nih.gov/pubmed/18759275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.23752
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