The p53 complex from monkey cells modulates the biochemical activities of simian virus 40 large T antigen.

We have compared the ATPase, DNA-binding, and helicase activities of free simian virus 40 (SV40) large T antigen (To) and T antigen complexed with cellular p53 (T+p53). Each activity is essential for productive viral infection. The T+p53 and To fractions were prepared by sequential immunosorption of...

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Pubblicato in:	J Virol
Autori principali:	Tack, L C, Wright, J H, Deb, S P, Tegtmeyer, P
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1989
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC247828/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2521675/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.63.3.1310-1317.1989
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