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The p53 complex from monkey cells modulates the biochemical activities of simian virus 40 large T antigen.

We have compared the ATPase, DNA-binding, and helicase activities of free simian virus 40 (SV40) large T antigen (To) and T antigen complexed with cellular p53 (T+p53). Each activity is essential for productive viral infection. The T+p53 and To fractions were prepared by sequential immunosorption of...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Tack, L C, Wright, J H, Deb, S P, Tegtmeyer, P
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1989
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC247828/
https://ncbi.nlm.nih.gov/pubmed/2521675
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