The p53 complex from monkey cells modulates the biochemical activities of simian virus 40 large T antigen.

We have compared the ATPase, DNA-binding, and helicase activities of free simian virus 40 (SV40) large T antigen (To) and T antigen complexed with cellular p53 (T+p53). Each activity is essential for productive viral infection. The T+p53 and To fractions were prepared by sequential immunosorption of...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Tack, L C, Wright, J H, Deb, S P, Tegtmeyer, P
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1989
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC247828/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2521675/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.63.3.1310-1317.1989
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