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Two overlapping sequence motifs within the polyomavirus enhancer are independently the targets of stimulation by both the tumor promoter 12-O-tetradecanoylphorbol-13-acetate and the Ha-ras oncogene.

A tumor-promoting phorbol ester, 12-O-tetradecanoylphorbol-13-acetate (TPA), strongly stimulates the activity of polyomavirus enhancer in a human erythroleukemia cell line, K562. The target of stimulation was the previously defined A element (from nucleotides 5107 to 5130) of the enhancer. We found...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Yamaguchi, Y, Satake, M, Ito, Y
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC247796/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2536818/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.63.3.1040-1048.1989
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