12-O-tetradecanoylphorbol-13-acetate activation of the MDR1 promoter is mediated by EGR1.
P-glycoprotein, the product of the MDR1 gene (multidrug resistance gene 1), is an energy-dependent efflux pump associated with treatment failure in some hematopoietic malignancies. Its expression is regulated during normal hematopoietic differentiation, although its function in normal hematopoietic...
Guardat en:
| Publicat a: | Mol Cell Biol |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Taylor & Francis
1995
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230861/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7565762/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.11.6100 |
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