12-O-tetradecanoylphorbol-13-acetate activation of the MDR1 promoter is mediated by EGR1.

P-glycoprotein, the product of the MDR1 gene (multidrug resistance gene 1), is an energy-dependent efflux pump associated with treatment failure in some hematopoietic malignancies. Its expression is regulated during normal hematopoietic differentiation, although its function in normal hematopoietic...

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Pubblicato in:	Mol Cell Biol
Autori principali:	McCoy, C, Smith, D E, Cornwell, M M
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 1995
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC230861/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7565762/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.15.11.6100
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