Hypoxia- and Vascular Endothelial Growth Factor-Induced Stromal Cell-Derived Factor-1α/CXCR4 Expression in Glioblastomas : One Plausible Explanation of Scherer’s Structures

The morphological patterns of glioma cell invasion are known as the secondary structures of Scherer. In this report, we propose a biologically based mechanism for the nonrandom formation of Scherer’s secondary structures based on the differential expression of stromal cell-derived factor (SDF)-1α an...

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Detalhes bibliográficos
Main Authors: Zagzag, David, Esencay, Mine, Mendez, Olga, Yee, Herman, Smirnova, Iva, Huang, Yuanyuan, Chiriboga, Luis, Lukyanov, Eugene, Liu, Mengling, Newcomb, Elizabeth W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2008
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2475791/
https://ncbi.nlm.nih.gov/pubmed/18599607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.071197
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