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HGF upregulates CXCR4 expression in gliomas via NF-κB: Implications for glioma cell migration

Invasion is a hallmark of malignant gliomas and is the main reason for therapeutic failure and recurrence of the tumor. CXCR4 is a key chemokine receptor implicated in glioma cell migration and whose expression is regulated by hypoxia. Here, we report that, hepatocyte growth factor (HGF) upregulated...

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Autori principali: Esencay, Mine, Newcomb, Elizabeth W., Zagzag, David
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3767998/
https://ncbi.nlm.nih.gov/pubmed/20157762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11060-010-0111-2
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