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A Genetic Screen for Increased Loss of Heterozygosity in Saccharomyces cerevisiae

Loss of heterozygosity (LOH) can be a driving force in the evolution of mitotic/somatic diploid cells, and cellular changes that increase the rate of LOH have been proposed to facilitate this process. In the yeast Saccharomyces cerevisiae, spontaneous LOH occurs by a number of mechanisms including c...

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Détails bibliographiques
Auteurs principaux: Andersen, Marguerite P., Nelson, Zara W., Hetrick, Elizabeth D., Gottschling, Daniel E.
Format: Artigo
Langue:Inglês
Publié: Genetics Society of America 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2475725/
https://ncbi.nlm.nih.gov/pubmed/18562670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.108.089250
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