Requirement of HDAC6 for Transforming Growth Factor-β1-induced Epithelial-Mesenchymal Transition

The aberrant expression of transforming growth factor (TGF)-β1 in the tumor microenvironment and fibrotic lesions plays a critical role in tumor progression and tissue fibrosis by inducing epithelial-mesenchymal transition (EMT). EMT promotes tumor cell motility and invasiveness. How EMT affects mot...

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Autori principali: Shan, Bin, Yao, Tso-pang, Nguyen, Hong T., Zhuo, Ying, Levy, Dawn R., Klingsberg, Ross C., Tao, Hui, Palmer, Michael L., Holder, Kevin N., Lasky, Joseph A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2008
Soggetti:
Mechanisms of Signal Transduction
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2475688/
https://ncbi.nlm.nih.gov/pubmed/18499657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M802786200
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