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The Epstein-Barr Virus Latent Membrane Protein 1 and Transforming Growth Factor–β1 Synergistically Induce Epithelial–Mesenchymal Transition in Lung Epithelial Cells

The histopathology of idiopathic pulmonary fibrosis (IPF) includes the presence of myofibroblasts within so-called fibroblastic foci, and studies suggest that lung myofibroblasts may be derived from epithelial cells through epithelial–mesenchymal transition (EMT). Transforming growth factor (TGF)–β1...

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Detalhes bibliográficos
Main Authors: Sides, Mark D., Klingsberg, Ross C., Shan, Bin, Gordon, Kristin A., Nguyen, Hong T., Lin, Zhen, Takahashi, Takashi, Flemington, Erik K., Lasky, Joseph A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3135845/
https://ncbi.nlm.nih.gov/pubmed/20693406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2009-0232OC
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