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Crystal Structure of the BARD1 Ankyrin Repeat Domain and Its Functional Consequences
BARD1 is the constitutive nuclear partner to the breast and ovarian cancer-specific tumor suppressor BRCA1. Together, they form a heterodimeric complex responsible for maintaining genomic stability through nuclear functions involving DNA damage signaling and repair, transcriptional regulation, and c...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2475683/ https://ncbi.nlm.nih.gov/pubmed/18480049 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M802333200 |
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