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The N-Terminal Domain of the Drosophila Retinoblastoma Protein Rbf1 Interacts with ORC and Associates with Chromatin in an E2F Independent Manner

BACKGROUND: The retinoblastoma (Rb) tumor suppressor protein can function as a DNA replication inhibitor as well as a transcription factor. Regulation of DNA replication may occur through interaction of Rb with the origin recognition complex (ORC). PRINCIPAL FINDINGS: We characterized the interactio...

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Detaylı Bibliyografya
Asıl Yazarlar: Ahlander, Joseph, Chen, Xiao-Bo, Bosco, Giovanni
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2008
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2475671/
https://ncbi.nlm.nih.gov/pubmed/18665226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0002831
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