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Distinct mechanisms of E2F regulation by Drosophila RBF1 and RBF2

RBF1, a Drosophila pRB family homolog, is required for cell cycle arrest and the regulation of E2F-dependent transcription. Here, we describe the properties of RBF2, a second family member. RBF2 represses E2F transcription and is present at E2F-regulated promoters. Analysis of in vivo protein comple...

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Autors principals: Stevaux, Olivier, Dimova, Dessislava, Frolov, Maxim V., Taylor-Harding, Barbie, Morris, Erick, Dyson, Nicholas
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC126297/
https://ncbi.nlm.nih.gov/pubmed/12234932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf501
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