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Acid-Promoted Cyclization Reactions of Tetrahydroindolinones. Model Studies for Possible Application in a Synthesis of Selaginoidine

The synthesis of various substituted bicyclic lactams by an acid-induced Pictet-Spengler reaction of tetrahydroindolinones bearing tethered heteroaromatic rings is presented. The outcome of the cyclization depends on the position of the furan tether, tether length, nature of the tethered heteroaroma...

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Detalhes bibliográficos
Main Authors: Rose, Mickea D., Cassidy, Michael P., Rashatasakhon, Paitoon, Padwa, Albert
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2475590/
https://ncbi.nlm.nih.gov/pubmed/17221972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo0619783
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