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ASSEMBLY, MATURATION, AND TRAFFICKING OF THE γ-SECRETASE COMPLEX IN ALZHEIMER’S DISEASE

In this review, we discuss the biology of γ-secretase, an enigmatic enzyme complex that is responsible for the generation of the amyloid-β peptide that constitutes the amyloid plaques of Alzheimer’s disease. We begin with a brief review on the processing of the amyloid precursor protein and a brief...

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Bibliografski detalji
Glavni autori: Dries, Daniel R., Yu, Gang
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2474811/
https://ncbi.nlm.nih.gov/pubmed/18393798
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