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Interaction of the Ras-related protein associated with diabetes Rad and the putative tumor metastasis suppressor NM23 provides a novel mechanism of GTPase regulation

Rad is the prototypic member of a new class of Ras-related GTPases. Purification of the GTPase-activating protein (GAP) for Rad revealed nm23, a putative tumor metastasis suppressor and a development gene in Drosophila. Antibodies against nm23 depleted Rad-GAP activity from human skeletal muscle cyt...

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Detalhes bibliográficos
Main Authors: Zhu, Jianhua, Tseng, Yu-Hua, Kantor, Jason D., Rhodes, Christopher J., Zetter, Bruce R., Moyers, Julie S., Kahn, C. Ronald
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC24747/
https://ncbi.nlm.nih.gov/pubmed/10611312
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