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Tumor metastasis suppressor nm23H1 regulates Rac1 GTPase by interaction with Tiam1

The putative tumor metastasis suppressor nm23H1 was originally identified in murine melanomas by subtraction cloning. It displays nucleoside diphosphate kinase activity and regulates cellular events, including growth and development. Recently nm23H1 has been reported to also act as a GTPase-activati...

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Detalhes bibliográficos
Main Authors: Otsuki, Yoshiro, Tanaka, Masamitsu, Yoshii, Shigeto, Kawazoe, Nobuko, Nakaya, Kazuyasu, Sugimura, Haruhiko
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC31844/
https://ncbi.nlm.nih.gov/pubmed/11274357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.071411598
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