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Insights into the biology and prevention of tumor metastasis provided by the Nm23 metastasis suppressor gene

Metastatic disease is the major cause of death among cancer patients. A class of genes, named metastasis suppressors, has been described to specifically regulate the metastatic process. The metastasis suppressor genes are downregulated in the metastatic lesion compared to the primary tumor. In this...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Cancer Metastasis Rev
Hauptverfasser: Marino, Natascia, Nakayama, Joji, Collins, Joshua W., Steeg, Patricia S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7479534/
https://ncbi.nlm.nih.gov/pubmed/22706779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10555-012-9374-8
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