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Nm23-H1 binds gelsolin and inactivates its actin-severing capacity to promote tumor cell motility and metastasis

Nm23-H1 has been identified as a metastasis suppressor gene but its protein interactions have yet to be understood with any mechanistic clarity. In this study, we evaluated the proteomic spectrum of interactions made by Nm23-H1 in 4T1 murine breast cancer cells derived from tissue culture, primary m...

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Detalhes bibliográficos
Main Authors: Marino, Natascia, Marshall, Jean-Claude, Collins, Joshua W., Zhou, Ming, Qian, Yongzhen, Veenstra, Timothy, Steeg, Patricia S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3825031/
https://ncbi.nlm.nih.gov/pubmed/23940300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-0368
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