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Nm23-H1 binds gelsolin and inactivates its actin-severing capacity to promote tumor cell motility and metastasis
Nm23-H1 has been identified as a metastasis suppressor gene but its protein interactions have yet to be understood with any mechanistic clarity. In this study, we evaluated the proteomic spectrum of interactions made by Nm23-H1 in 4T1 murine breast cancer cells derived from tissue culture, primary m...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3825031/ https://ncbi.nlm.nih.gov/pubmed/23940300 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-0368 |
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