Subnanometer-resolution electron cryomicroscopy-based domain models for the cytoplasmic region of skeletal muscle RyR channel

The skeletal muscle Ca(2+) release channel (RyR1), a homotetramer, regulates the release of Ca(2+) from the sarcoplasmic reticulum to initiate muscle contraction. In this work, we have delineated the RyR1 monomer boundaries in a subnanometer-resolution electron cryomicroscopy (cryo-EM) density map....

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Detalhes bibliográficos
Main Authors: Serysheva, Irina I., Ludtke, Steven J., Baker, Matthew L., Cong, Yao, Topf, Maya, Eramian, David, Sali, Andrej, Hamilton, Susan L., Chiu, Wah
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2474495/
https://ncbi.nlm.nih.gov/pubmed/18621707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0803189105
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