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Glucose intolerance caused by a defect in the entero-insular axis: A study in gastric inhibitory polypeptide receptor knockout mice
Mice with a targeted mutation of the gastric inhibitory polypeptide (GIP) receptor gene (GIPR) were generated to determine the role of GIP as a mediator of signals from the gut to pancreatic β cells. GIPR−/− mice have higher blood glucose levels with impaired initial insulin response after oral gluc...
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主要な著者: | , , , , , , , , , , , , , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
出版事項: |
The National Academy of Sciences
1999
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC24735/ https://ncbi.nlm.nih.gov/pubmed/10611300 |
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