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Glucose intolerance caused by a defect in the entero-insular axis: A study in gastric inhibitory polypeptide receptor knockout mice

Mice with a targeted mutation of the gastric inhibitory polypeptide (GIP) receptor gene (GIPR) were generated to determine the role of GIP as a mediator of signals from the gut to pancreatic β cells. GIPR−/− mice have higher blood glucose levels with impaired initial insulin response after oral gluc...

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Detalhes bibliográficos
Main Authors: Miyawaki, Kazumasa, Yamada, Yuichiro, Yano, Hideki, Niwa, Hitoshi, Ban, Nobuhiro, Ihara, Yu, Kubota, Akira, Fujimoto, Shinpei, Kajikawa, Mariko, Kuroe, Akira, Tsuda, Kinsuke, Hashimoto, Hiroyuki, Yamashita, Tokuyuki, Jomori, Takahito, Tashiro, Fumi, Miyazaki, Jun-ichi, Seino, Yutaka
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC24735/
https://ncbi.nlm.nih.gov/pubmed/10611300
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