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A viable mouse model of factor X deficiency provides evidence for maternal transfer of factor X
Background:Activated factor X (FXa) is a vitamin K-dependent serine protease that plays a pivotal role in blood coagulation by converting prothrombin to thrombin. There are no reports of humans with complete deficiency of FX, and knockout of murine F10 is embryonic or perinatal lethal. Objective:We...
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| Asıl Yazarlar: | , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Blackwell Publishing Ltd
2008
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2471867/ https://ncbi.nlm.nih.gov/pubmed/18036190 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1538-7836.2008.02849.x |
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