A viable mouse model of factor X deficiency provides evidence for maternal transfer of factor X

Background:Activated factor X (FXa) is a vitamin K-dependent serine protease that plays a pivotal role in blood coagulation by converting prothrombin to thrombin. There are no reports of humans with complete deficiency of FX, and knockout of murine F10 is embryonic or perinatal lethal. Objective:We...

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Detalhes bibliográficos
Main Authors: TAI, S J, HERZOG, R W, MARGARITIS, P, ARRUDA, V R, CHU, K, GOLDEN, J A, LABOSKY, P A, HIGH, K A
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2008
Assuntos:
Coagulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2471867/
https://ncbi.nlm.nih.gov/pubmed/18036190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1538-7836.2008.02849.x
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