Convergence of two repressors through heterodimer formation of androgen receptor and testicular orphan receptor-4: A unique signaling pathway in the steroid receptor superfamily

The androgen receptor (AR) binds to androgen response elements and regulates target genes via a mechanism involving coregulators. Here we demonstrate that the AR can interact with the testicular orphan receptor-4 (TR4) and function as a repressor to down-regulate the TR4 target genes by preventing t...

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Bibliographische Detailangaben
Hauptverfasser: Lee, Yi-Fen, Shyr, Chih-Rong, Thin, Tin Htwe, Lin, Wen-Jye, Chang, Chawnshang
Format: Artigo
Sprache:Inglês
Veröffentlicht: The National Academy of Sciences 1999
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC24715/
https://ncbi.nlm.nih.gov/pubmed/10611280
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