Convergence of two repressors through heterodimer formation of androgen receptor and testicular orphan receptor-4: A unique signaling pathway in the steroid receptor superfamily

The androgen receptor (AR) binds to androgen response elements and regulates target genes via a mechanism involving coregulators. Here we demonstrate that the AR can interact with the testicular orphan receptor-4 (TR4) and function as a repressor to down-regulate the TR4 target genes by preventing t...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Lee, Yi-Fen, Shyr, Chih-Rong, Thin, Tin Htwe, Lin, Wen-Jye, Chang, Chawnshang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1999
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24715/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10611280/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.26.14724
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