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Convergence of two repressors through heterodimer formation of androgen receptor and testicular orphan receptor-4: A unique signaling pathway in the steroid receptor superfamily
The androgen receptor (AR) binds to androgen response elements and regulates target genes via a mechanism involving coregulators. Here we demonstrate that the AR can interact with the testicular orphan receptor-4 (TR4) and function as a repressor to down-regulate the TR4 target genes by preventing t...
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Main Authors: | , , , , |
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Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
The National Academy of Sciences
1999
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC24715/ https://ncbi.nlm.nih.gov/pubmed/10611280 |
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