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Scanning mutagenesis of the putative transmembrane segments of K(ir)2.1, an inward rectifier potassium channel

Structural models of inward rectifier K(+) channels incorporate four identical or homologous subunits, each of which has two hydrophobic segments (M1 and M2) which are predicted to span the membrane as α helices. Since hydrophobic interactions between proteins and membrane lipids are thought to be g...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Collins, Anthony, Chuang, Huai-hu, Jan, Yuh Nung, Jan, Lily Yeh
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1997
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24700/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9144259/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.10.5456
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