Loading...

Evidence that the nucleotide exchange and hydrolysis cycle of G proteins causes acute desensitization of G-protein gated inward rectifier K(+) channels

The G-protein gated inward rectifier K(+) channel (GIRK) is activated in vivo by the Gβγ subunits liberated upon G(i)-coupled receptor activation. We have recapitulated the acute desensitization of receptor-activated GIRK currents in heterologous systems and shown that it is a membrane-delimited pro...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Chuang, Huai-hu, Yu, Mei, Jan, Yuh Nung, Jan, Lily Yeh
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1998
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC21708/
https://ncbi.nlm.nih.gov/pubmed/9751733
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!