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Stabilization of ion selectivity filter by pore loop ion pairs in an inwardly rectifying potassium channel
Ion selectivity is critical for the biological functions of voltage-dependent cation channels and is achieved by specific ion binding to a pore region called the selectivity filter. In voltage-gated K(+), Na(+) and Ca(2+) channels, the selectivity filter is formed by a short polypeptide loop (called...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The National Academy of Sciences of the USA
1997
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC19832/ https://ncbi.nlm.nih.gov/pubmed/9037094 |
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