Stabilization of ion selectivity filter by pore loop ion pairs in an inwardly rectifying potassium channel
Ion selectivity is critical for the biological functions of voltage-dependent cation channels and is achieved by specific ion binding to a pore region called the selectivity filter. In voltage-gated K(+), Na(+) and Ca(2+) channels, the selectivity filter is formed by a short polypeptide loop (called...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1997
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC19832/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9037094/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.4.1568 |
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