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Scanning mutagenesis of the putative transmembrane segments of K(ir)2.1, an inward rectifier potassium channel

Structural models of inward rectifier K(+) channels incorporate four identical or homologous subunits, each of which has two hydrophobic segments (M1 and M2) which are predicted to span the membrane as α helices. Since hydrophobic interactions between proteins and membrane lipids are thought to be g...

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Autori principali: Collins, Anthony, Chuang, Huai-hu, Jan, Yuh Nung, Jan, Lily Yeh
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1997
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC24700/
https://ncbi.nlm.nih.gov/pubmed/9144259
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