Conservation of the Drosophila lateral inhibition pathway in human lung cancer: A hairy-related protein (HES-1) directly represses achaete-scute homolog-1 expression

The achaete-scute genes encode essential transcription factors in normal Drosophila and vertebrate nervous system development. Human achaete-scute homolog-1 (hASH1) is constitutively expressed in a human lung cancer with neuroendocrine (NE) features, small cell lung cancer (SCLC), and is essential f...

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Hlavní autoři: Chen, Herbert, Thiagalingam, Arunthathi, Chopra, Hemi, Borges, Michael W., Feder, John N., Nelkin, Barry D., Baylin, Stephen B., Ball, Douglas W.
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences of the USA 1997
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC24682/
https://ncbi.nlm.nih.gov/pubmed/9144241
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