Conservation of the Drosophila lateral inhibition pathway in human lung cancer: A hairy-related protein (HES-1) directly represses achaete-scute homolog-1 expression

The achaete-scute genes encode essential transcription factors in normal Drosophila and vertebrate nervous system development. Human achaete-scute homolog-1 (hASH1) is constitutively expressed in a human lung cancer with neuroendocrine (NE) features, small cell lung cancer (SCLC), and is essential f...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Chen, Herbert, Thiagalingam, Arunthathi, Chopra, Hemi, Borges, Michael W., Feder, John N., Nelkin, Barry D., Baylin, Stephen B., Ball, Douglas W.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1997
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24682/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9144241/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.10.5355
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