Unconventional function of an Achaete-Scute homolog as a terminal selector of nociceptive neuron identity.
Proneural genes are among the most early-acting genes in nervous system development, instructing blast cells to commit to a neuronal fate. Drosophila Atonal and Achaete-Scute complex (AS-C) genes, as well as their vertebrate orthologs, are basic helix-loop-helix (bHLH) transcription factors with suc...
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| Principais autores: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science (PLoS)
2018-04-01
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| Serier: | PLoS Biology |
| Online adgang: | https://doi.org/10.1371/journal.pbio.2004979 |
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