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Achaete-Scute Complex Homolog 1 Regulates Tumor-Initiating Capacity in Human Small Cell Lung Cancer

The basic helix-loop-helix transcription factor ASCL1 (Achaete-scute complex homolog-1) is essential for the development of normal lung neuroendocrine (NE) cells as well as other endocrine and neural tissues. SCLC and NSCLC with NE features express ASCL1, where the factor may play a role in the viru...

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Detalhes bibliográficos
Main Authors: Jiang, Tianyun, Collins, Brendan J., Jin, Ning, Watkins, David N., Brock, Malcolm V., Matsui, William, Nelkin, Barry D., Ball, Douglas W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919317/
https://ncbi.nlm.nih.gov/pubmed/19176379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-2762
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