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B cell receptor revision diminishes the autoreactive B cell response after antigen activation in mice
Autoreactive B cells are regulated in the BM during development through mechanisms, including editing of the B cell receptor (BCR), clonal deletion, and anergy. Peripheral B cell tolerance is also important for protection from autoimmune damage, although the mechanisms are less well defined. Here we...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2008
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2467385/ https://ncbi.nlm.nih.gov/pubmed/18636122 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI35618 |
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