The structural basis for activation of the Rab Ypt1p by the TRAPP membrane tethering complexes

The multimeric membrane tethering complexes TRAPPI and TRAPPII share seven subunits, of which four (Bet3p, Bet5p, Trs23p, and Trs31p) are minimally needed to activate the Rab GTPase Ypt1p in an event preceding membrane fusion. Here we present the structure of a heteropentameric TRAPPI assembly compl...

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Autori principali: Cai, Yiying, Chin, Harvey F., Lazarova, Darina, Menon, Shekar, Fu, Chunmei, Cai, Huaqing, Sclafani, Anthony, Rodgers, David W., De La Cruz, Enrique M., Ferro-Novick, Susan, Reinisch, Karin M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2465810/
https://ncbi.nlm.nih.gov/pubmed/18585354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.04.049
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