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Establishing a Role for the GTPase Ypt1p at the Late Golgi

GTPases of the Rab family cycle between an inactive (GDP-bound) and active (GTP-bound) conformation. The active form of the Rab regulates a variety of cellular functions via multiple effectors. Guanine nucleotide exchange factors (GEFs) activate Rabs by accelerating the exchange of GDP for GTP, whil...

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Autors principals: Sclafani, Anthony, Chen, Shuliang, Rivera-Molina, Felix, Reinisch, Karin, Novick, Peter, Ferro-Novick, Susan
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2861988/
https://ncbi.nlm.nih.gov/pubmed/20059749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-0854.2010.01031.x
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