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Kinetic Analysis of the Guanine Nucleotide Exchange Activity of TRAPP, a Multimeric Ypt1p Exchange Factor

The TRAPP complexes, large multimeric assemblies that function in membrane traffic, are guanine nucleotide exchange factors (GEF) that activate the Rab GTPase Ypt1p. Here we measured the rate and equilibrium constants that define the interaction of Ypt1p with guanine nucleotide (GDP and GTP/GMPPNP)...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Chin, Harvey F., Cai, Yiying, Menon, Shekar, Ferro-Novick, Susan, Reinisch, Karin M., De La Cruz, Enrique M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2770256/
https://ncbi.nlm.nih.gov/pubmed/19361519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.03.068
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